Each chapter contains strategically positioned sections that cover important skills. In each section, an important skill is developed or fine-tuned. Multiple problems are then provided in order to build competence in that skill. Students are given the opportunity to master each core skill before moving on to the next section. The end-of-chapter exercises integrate the skills developed throughout the chapter. Three short chapters (Chapters 7, 12, and 24) are devoted entirely to skill development (proposing mechanisms and proposing syntheses). WileyPLUS incorporates hundreds of end of chapter problems all of which are available with multiple forms of problem solving support (link to text, tutorials, videos, etc.). Dr. Klein's writing style strikes a unique balance between a formal and conversational tone, while not comprising the scientific rigor expected of a 2-semester organic chemistry text.

1 A Review of General Chemistry: Electrons, Bonds, and Molecular Properties

2 Molecular Representations

3 Acids and Bases

4 Alkanes and Cycloalkanes

5 Stereoisomerism

6 Chemical Reactivity and Mechanisms

7 Substitution Reactions

8 Alkenes: Structure and Preparation via Elimination Reactions

9 Addition Reactions of Alkenes

10 Alkynes

11 Radical Reactions

12 Synthesis

13 Alcohols and Phenols

14 Ethers and Epoxides; Thiols and Sulfides

15 Infrared Spectroscopy and Mass Spectrometry

16 Nuclear Magnetic Resonance Spectroscopy

17 Conjugated Pi Systems and Pericyclic Reactions

18 Aromatic Compounds

19 Aromatic Substitution Reactions

20 Aldehydes and Ketones

21 Carboxylic Acids and Their Derivatives

22 Alpha Carbon Chemistry: Enols and Enolates

23 Amines

24 Carbohydrates

25 Amino Acids, Peptides, and Proteins

26 Lipids

27 Synthetic Polymers