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Summary

Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida*Opioids in Preclinical and Clinical Traials; by K. Kawai and S. Sakami*Twin and Triplet Drugs in Opioid; by H. Fujii *Synthesis of Neoclerodane Diterpenes (Salvinorin Derivatives) and Their Pharmacological Effects; by T. E. Prisinzano*Synthesis of Novel Basic Opioid Skeletons Derived from Naltrexone; by H. Nagase *Nonpeptidic d Opioid Agonists: What Have We Learned?; by S. N. Calderson*Synthesis of 14-Alkoxy- and 14-Aminomorphinan Derivatives and Their Pharmacological Actions ; by H. Schmidhammer and M. Spetea *Development of Novel Opioid Mimetics, Agonists and Antagonists ; by Y. Okada and Y. Tsuda*3D-Pharmacophore Identification for k Opioid Agonists Using Ligand-Based Drug Design Techniques; by N. Yamaotsu and S. Hironi

Table of Contents

Recent Advances in the Synthesis of Morphine and Related Alkaloidsp. 1
Opioids in Preclinical and Clinical Trialsp. 29
Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actionsp. 63
14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actionsp. 93
Nonpeptidic Delta (¿) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?p. 121
Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effectsp. 141
Synthesis of Novel Basic Skeletons Derived from Naltrexonep. 187
Twin and Triplet Drugs in Opioid Researchp. 239
3D-Pharmacophore Identification for K-Opioid Agonists Using Ligand-Based Drug-Design Techniquesp. 277
Indexp. 309
Table of Contents provided by Ingram. All Rights Reserved.

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