Introduction to Conservation Genetics

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Format: Paperback
Pub. Date: 2002-04-15
Publisher(s): Cambridge University Press
List Price: $89.25

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Summary

The biological diversity of our planet is being depleted due to the direct and indirect consequences of human activity. As the size of animal and plant populations decrease, loss of genetic diversity reduces their ability to adapt to changes in the environment, with inbreeding depression an inevitable consequence for many species. This textbook provides a clear and comprehensive introduction to the importance of genetic studies in conservation. The text is presented in an easy-to-follow format with main points and terms clearly highlighted. Each chapter concludes with a concise summary, which, together with worked examples and problems and answers, emphasise the key principles covered. Text boxes containing interesting case studies and other additional information enrich the content throughout, and over 100 beautiful pen and ink portraits of endangered species help bring the material to life.

Table of Contents

Preface xiii
Copyright acknowledgments xx
Introduction
1(22)
`The sixth extinction'
2(1)
Why conserve biodiversity?
2(1)
Endangered and extinct species
3(3)
What is an endangered species?
6(1)
What causes extinctions?
7(2)
Recognition of genetic factors in conservation biology
9(1)
What is conservation genetics?
9(2)
How is genetics used to minimize extinctions?
11(5)
Genetic versus demographic and environmental factors in conservation biology
16(1)
What do we need to know to genetically manage threatened species?
16(2)
Methodology in conservation genetics
18(1)
Island theme
19(1)
Sources of information
19(1)
Summary
19(1)
General bibliography
20(1)
Problems
21(1)
Practical exercises: Categorizing endangement of species
22(1)
Genetics and extinction
23(22)
Genetics and the fate of endangered species
24(3)
Relationship between inbreeding and extinction
27(2)
Inbreeding and extinction in the wild
29(7)
Relationship between loss of genetic diversity and extinction
36(3)
Summary
39(1)
Further reading
39(1)
Problems
40(1)
Practical exercises: Computer projections
40(5)
SECTION I EVOLUTIONARY GENETICS OF NATURAL POPULATIONS
Genetic diversity
45(27)
Importance of genetic diversity
46(1)
What is genetic diversity?
47(3)
Measuring genetic diversity
50(10)
Extent of genetic diversity
60(6)
Low genetic diversity in endangered species
66(1)
What genetic diversity determines evolutionary potential?
67(1)
Variation over space and time
67(1)
What explains differences in levels of genetic diversity?
68(1)
Genetic differences among species
68(1)
Summary
68(1)
Further reading
69(1)
Problems
70(1)
Practical exercise: Measuring genetic diversity using microsatellites
70(2)
Characterizing genetic diversity: single loci
72(24)
Describing genetic diversity
73(1)
Frequencies of alleles and genotypes
73(2)
Hardy-Weinberg equilibrium
75(3)
Expected heterozygosity
78(6)
Deviations from Hardy-Weinberg equilibrium
84(2)
Extensions of the Hardy-Weinberg equilibrium
86(4)
More than one locus-linkage disequilibrium
90(3)
Summary
93(1)
Further reading
94(1)
Problems
94(2)
Characterizing genetic diversity: quantitative variation
96(30)
Importance of quantitative characters
97(1)
Properties of quantitative characters
98(2)
Basis of quantitative genetic variation
100(3)
Methods for detecting quantitative genetic variation
103(2)
Partitioning genetic and environmental variation
105(1)
Genotype X environment interaction
106(2)
The need for contemporary comparisons and control populations
108(1)
Partitioning of quantitative genetic variation
108(3)
Evolutionary potential and heritability
111(9)
Susceptibility to inbreeding depression
120(2)
Correlations between molecular and quantitative genetic variation
122(1)
Organization of quantitative genetic variation
122(1)
Summary
123(1)
Further reading
123(1)
Problems
124(2)
Evolution in large populations. I. Natural selection and adaptation
126(28)
The need to evolve
127(4)
Factors controlling the evolution of populations
131(2)
Selection
133(12)
Selection on quantitative characters
145(1)
Directional selection
146(3)
Stabilizing selection
149(1)
Disruptive selection
149(1)
Summary
150(1)
Further reading
150(1)
Problems
151(1)
Practical exercises: Computer simulations
152(2)
Evolution in large populations. II. Mutation, migration and their interactions with selection
154(21)
Factors controlling the evolution of populations
155(1)
Importance of mutation, migration and their interactions with selection in conservation
155(1)
Origin and regeneration of genetic diversity
155(1)
Mutation
156(4)
Selective value of mutations
160(2)
Mutation-selection balance and the mutation load
162(5)
Migration
167(2)
Migration-selection equilibria and clines
169(4)
Summary
173(1)
Further reading
173(1)
Problems
173(2)
Evolution in small populations
175(22)
Importance of small populations in conservation biology
176(2)
Impact of small population size: chance effects
178(9)
Inbreeding
187(1)
Measuring population size
187(3)
Selection in small populations
190(1)
Mutation in small populations
191(1)
Mutation-selection equilibrium in small populations
192(1)
Computer simulation
193(1)
Summary
194(1)
Further reading
194(1)
Problems
195(1)
Practical exercises: Computer simulations
195(2)
Maintenance of genetic diversity
197(30)
Conservation of genetic diversity
198(1)
Fate of different classes of mutations
198(1)
Maintenance of genetic diversity in large populations
199(1)
Neutral mutations under random genetic drift
200(3)
Selection intensities vary among characters
203(1)
Balancing selection
204(10)
Maintenance of genetic diversity in small populations
214(7)
Summary
221(1)
Further reading
221(1)
Problems
222(1)
Practical exercises: Computer simulations
223(4)
SECTION II EFFECTS OF POPULATION SIZE REDUCTION
Loss of genetic diversity in small populations
227(27)
Changes in genetic diversity over time
228(1)
Relationship between loss of genetic diversity and reduced fitness
229(2)
Effects of sustained population size restrictions on genetic diversity
231(4)
Relationship between population size and genetic diversity in wild populations
235(4)
Effective population size
239(2)
Measuring effective population size
241(10)
Summary
251(1)
Further reading
252(1)
Problems
252(1)
Practical exercises: Computer simulations
253(1)
Inbreeding
254(26)
What is inbreeding?
255(1)
Conservation concerns with inbreeding
256(1)
Inbreeding coefficient (F)
256(2)
Genetic consequences of inbreeding
258(5)
Inbreeding in small populations
263(6)
Pedigrees
269(2)
Breeding systems in nature
271(1)
Regular systems of inbreeding
271(3)
Mutation-selection balance with inbreeding
274(2)
Inbreeding in polyploids
276(1)
Relationship between inbreeding, heterozygosity, genetic diversity and population size
277(1)
Summary
278(1)
Further reading
278(1)
Problems
279(1)
Inbreeding depression
280(29)
Inbreeding depression in naturally outbreeding species
281(1)
Inbreeding depression in the wild
282(3)
Inbreeding depression due to small population size
285(1)
Inbreeding and extinction
286(1)
Characteristics of inbreeding depression
287(3)
Genetic basis of inbreeding depression
290(5)
Purging
295(4)
Detecting and measuring inbreeding depression
299(3)
Inbreeding and population viability
302(3)
Recovering from inbreeding depression
305(2)
Summary
307(1)
Further reading
307(1)
Problems
308(1)
Population fragmentation
309(27)
Habitat fragmentation
310(1)
Population fragmentation
310(2)
Population structure
312(2)
Completely isolated population fragments
314(10)
Measuring population fragmentation: F statistics
324(3)
Gene flow among population fragments
327(3)
Measuring gene flow
330(2)
Impacts of different population structures on reproductive fitness
332(1)
Summary
333(1)
Further reading
334(1)
Problems
334(2)
Genetically viable populations
336(29)
Shortage of space for threatened species
337(2)
How large?
339(1)
Retaining reproductive fitness
339(2)
Retaining evolutionary potential
341(2)
How large are threatened populations?
343(1)
What happens to species with Ne <500?
344(4)
Retaining single locus diversity in the long term
348(1)
Time to regenerate genetic diversity
349(1)
Avoiding accumulation of new deleterious mutations
349(2)
Genetic goals in the management of wild populations
351(1)
Genetic goals in management of captive populations-a compromise
352(4)
The fallacy of small surviving populations
356(1)
Summary
357(1)
Further reading
358(1)
Problems
358(7)
SECTION III FROM THEORY TO PRACTICE
Resolving taxonomic uncertainties and defining management units
365(30)
Importance of accurate taxonomy in conservation biology
366(4)
What is a species?
370(1)
Sub-species
371(1)
Higher taxonomic categories
371(1)
How do species arise?
372(3)
Use of genetic markers in delineation of sympartic species
375(1)
Use of genetic markers in delineation of allopatric species
376(3)
Measuring differences between populations: genetic distance
379(3)
Constructing phylogenetic trees
382(3)
Outbreeding depression
385(3)
Defining management units within species
388(4)
Summary
392(1)
Further reading
392(1)
Problems
393(1)
Practical exercise: Building a phylogenetic tree
394(1)
Genetics and the management of wild populations
395(24)
Genetic issues in wild populations
396(3)
Resolving taxonomy and management units
399(1)
Increasing population size
399(2)
Diagnosing genetic problems
401(1)
Recovering small inbred populations with low genetic diversity
401(3)
Genetic management of fragmented populations
404(6)
Genetic issues in reserve design
410(1)
Introgression and hybridization
411(1)
Impacts of harvesting
412(2)
Genetic management of species that are not outbreeding diploids
414(2)
Summary
416(1)
Further reading
417(1)
Problems
417(2)
Genetic management of captive populations
419(29)
Why captive breed?
420(2)
Stages in captive breeding and reintroduction
422(1)
Founding captive populations
423(3)
Growth of captive populations
426(1)
Genetic management of captive populations
427(2)
Current genetic management of captive populations
429(10)
Captive management of groups
439(2)
Ex situ conservation of plants
441(1)
Reproductive technology and genome resource banks
441(2)
Managing inherited diseases in endangered species
443(2)
Summary
445(1)
Further reading
446(1)
Problems
446(2)
Genetic management for reintroduction
448(23)
Reintroductions
449(3)
Genetic changes in captivity that affect reintroduction success
452(1)
Genetic adaptation to captivity
452(7)
Genetic management of reintroductions
459(4)
How successful are reintroductions?
463(2)
Supportive breeding
465(1)
Case studies in captive breeding and reintroduction
466(3)
Summary
469(1)
Further reading
470(1)
Problems
470(1)
Use of molecular genetics in forensics and to understand species biology
471(31)
Forensics: detecting illegal hunting and collecting
472(2)
An understanding of species' biology is critical to its conservation
474(1)
Gene trees and coalescence
475(5)
Population size and demographic history
480(5)
Gene flow and population structure
485(6)
Reintroduction and translocation
491(1)
Reproduction parentage, founder relationships and sexing
492(6)
Disease
498(1)
Diet
499(1)
Summary
499(1)
Further reading
500(1)
Problems
500(2)
The broader context: population viability analysis (PVA)
502(27)
What causes endangerment and extinction?
503(3)
Predicting extinction probabilities: population viability analysis (PVA)
506(10)
Recovering threatened populations
516(4)
How useful are the predictions of PVA?
520(3)
Lessons learned
523(1)
Minimum viable population sizes (MVP)
524(2)
Summary
526(1)
Further reading
526(1)
Problems
527(1)
Practical exercises: Population viability analyses
527(2)
Take home messages from this book 529(2)
Revision problems 531(2)
Glossary 533(13)
Answers to problems 546(21)
References 567(40)
Index 607

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